Service

Analysis Service

The Genome Sequence Informatics (GSI) Team within IBC offers tools and workflows for sequence analysis and quality control. The team has extensive expertise in a wide variety of cancer sequence data types from various next-generation sequencing platforms. Using highly automated and reproducible workflows, GSI provides both primary and secondary analyses, and can also perform bespoke analysis using specific cutting-edge software. Our analysis team provides assistance with experimental design, as well as the interpretation and the publication of experimental results. Data storage and secure transfer or sharing options can also be provided.

SOME OF THE SERVICES WE PROVIDE ARE:

  • Analysis and variant calling of wide range of samples including FFPE
  • Various types of RNA-seq
  • ATAC-seq
  • ChIP-seq
  • Methylation analysis
  • Integration of public data sets
  • Pathway and other functional analysis

For a quote please contact morgan.taschuk@oicr.on.ca.

EXAMPLE PUBLICATIONS SUPPORTED BY THE TEAM

  • Fraser M, Sabelnykova VY, Yamaguchi TN, Heisler LE, Livingstone J, Huang V, Shiah YJ, Yousif F, Lin X, Masella AP, Fox NS, Xie M, Prokopec SD, Berlin A, Lalonde E, Ahmed M, Trudel D, Luo X, Beck TA, Meng A, Zhang J, D’Costa A, Denroche RE, Kong H, Espiritu SM, Chua ML, Wong A, Chong T, Sam M, Johns J, Timms L, Buchner NB, Orain M, Picard V, Hovington H8, Murison A, Kron K, Harding NJ, P’ng C, Houlahan KE, Chu KC, Lo B, Nguyen F, Li CH, Sun RX, de Borja R, Cooper CI, Hopkins JF, Govind SK, Fung C, Waggott D, Green J, Haider S, Chan-Seng-Yue MA, Jung E, Wang Z, Bergeron A, Pra AD, Lacombe L, Collins CC, Sahinalp C, Lupien M, Fleshner NE, He HH, Fradet Y, Tetu B, van der Kwast T, McPherson JD, Bristow RG, Boutros PC. .Genomic hallmarks of localized, non-indolent prostate cancer. Nature 2017.

  • Alioto, et. al. A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing. Nature Communications 6:10001 (PMID: 26647970)

Contact The Genome Sequence Informatics Team

Morgan Taschuk

Director, Genome Sequence Informatics

Genome Sequence Informatics

morgan.taschuk at oicr.on.ca

Ontario Institute for Cancer Research (OICR)

MaRS Centre
661 University Avenue
Toronto, Ontario M5G 0A3
Canada